Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2508203 | 1.00 | KCNH2 (0.62) | KCNH2SLC2A1 | |
| SCHEMBL2503540 | 0.95 | KCNH2 (0.56) | KCNH2SLC2A1 | |
| SCHEMBL2521451 | 0.95 | KCNH2 (0.62) | KCNH2 | |
| SCHEMBL9981322 | 0.94 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL2505146 | 0.94 | SLC2A1 (0.66) | KCNH2SLC2A1 | |
| SCHEMBL2509566 | 0.94 | SLC2A1 (0.66) | KCNH2SLC2A1 | |
| SCHEMBL2506514 | 0.93 | SLC2A1 (0.57) | KCNH2SLC2A1 | |
| SCHEMBL2502355 | 0.93 | SLC2A1 (0.57) | KCNH2SLC2A1 | |
| SCHEMBL2498647 | 0.93 | KCNH2 (0.58) | KCNH2SLC2A1 | |
| SCHEMBL9981194 | 0.92 | KCNH2 (0.56) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376497-A1 | 5-AMINO-2-(1-HYDROXY-ETHYL)-TETRAHYDROPYRAN DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010067332-A1 | 5-AMINO-2-(1-HYDROXY-ETHYL)-TETRAHYDROPYRAN DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-06-17 | — | — | WO | disclosed |