Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12812465 | 0.87 | NPC1 (0.50) | KDM4EALDH1A1NPC1HSP90AA1L3MBTL1 | |
| Formamide SCHEMBL19579786 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1NPC1HSP90AA1L3MBTL1 | |
| SCHEMBL12914543 | 0.81 | KDM4E (0.75) | KDM4EALDH1A1NPC1HSP90AA1L3MBTL1 | |
| SCHEMBL19233664 | 0.74 | HSP90AA1 (0.45) | KDM4EALDH1A1NPC1HSP90AA1L3MBTL1 | |
| SCHEMBL1707885 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1NPC1HSP90AA1L3MBTL1 | |
| SCHEMBL2521419 | 0.73 | KDM4E (1.00) | KDM4EALDH1A1NPC1NCOA1MAPT | |
| SCHEMBL30947375 | 0.73 | KDM4E (1.00) | KDM4EALDH1A1NPC1NCOA1MAPT | |
| SCHEMBL30863308 | 0.73 | KDM4E (1.00) | KDM4EALDH1A1NPC1NCOA1MAPT | |
| SCHEMBL11218315 | 0.72 | KDM4E (0.47) | KDM4EALDH1A1CYP19A1 | |
| SCHEMBL8558621 | 0.72 | KDM4E (0.67) | KDM4EALDH1A1NPC1NCOA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022267945-A1 | METHOD FOR PREPARING PRANOPROFEN AND COMPOSITION CONTAINING PRANOPROFEN AND IMPURITY | 沈阳兴齐眼药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |