Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11754961 | 0.95 | — | — | |
| Bromide SCHEMBL760445 | 0.68 | — | — | |
| Bromide SCHEMBL28737968 | 0.67 | — | — | |
| SCHEMBL1994101 | 0.67 | — | — | |
| SCHEMBL1936538 | 0.64 | — | — | |
| SCHEMBL22537 | 0.64 | — | — | |
| Bromide SCHEMBL28278318 | 0.64 | — | — | |
| SCHEMBL2153288 | 0.64 | TSHR (1.00) | — | |
| Bromide SCHEMBL25265853 | 0.64 | — | — | |
| SCHEMBL12075585 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10577460-B2 | Method for producing polyester | NIPPON SODA CO., LTD. (JP) | 2020-03-03 | — | — | US | disclosed |
| US-20180022867-A1 | METHOD FOR PRODUCING POLYESTER | NIPPON SODA CO., LTD. (JP) | 2018-01-25 | — | — | US | disclosed |
| EP-3248998-A1 | METHOD FOR PRODUCING POLYESTER | Nippon Soda Co., Ltd. (JP) | 2017-11-29 | — | — | EP | disclosed |
| EP-2588469-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF PI3K ACTIVITY | Amgen Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| US-20130096134-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2013-04-18 | — | — | US | disclosed |
| WO-2012003271-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF PI3K ACTIVITY | AMGEN INC. (US) | 2012-01-05 | — | — | WO | disclosed |