SCHEMBL24825786

SCHEMBL24825786

c1ccc2c(N(c3ccc(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)cc3)c3ccc4ccc5c6ccccc6oc5c4c3)cccc2c1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP1A1 P04798 2/20 0.31
CYP1B1 Q16678 2/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24825788 0.97 KDM4E (0.33) ALOX5KDM4EATML3MBTL1
SCHEMBL24825776 0.95 CYP1A1 (0.32) ALOX5KDM4EATML3MBTL1CYP1A1
SCHEMBL24825130 0.94 CYP1A1 (0.32) KDM4EATML3MBTL1CYP1A1CYP1B1
SCHEMBL24826650 0.93 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL24826652 0.93 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL24825891 0.93 CYP1A1 (0.33) KDM4EATML3MBTL1CYP1A1CYP1B1
SCHEMBL24827026 0.93 KDM4E (0.34) ALOX5KDM4EATML3MBTL1
SCHEMBL24825063 0.92 KDM4E (0.32) KDM4EATML3MBTL1CYP1A1CYP1B1
SCHEMBL24825553 0.91 SIRT2 (0.34) KDM4EATML3MBTL1CYP1A1CYP1B1
SCHEMBL24826618 0.91 KDM4E (0.33) ALOX5KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416174-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-12-29 US disclosed