SCHEMBL24825890

SCHEMBL24825890

c1ccc2c(N(c3ccc(-n4c5ccccc5c5ccccc54)cc3)c3ccc4c(c3)oc3c5ccccc5ccc43)cccc2c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP1A1 P04798 6/20 0.32
CYP1B1 Q16678 6/20 0.32
CYP1A2 P05177 5/20 0.32
KMT2A Q03164 1/20 0.32
DYRK1A Q13627 1/20 0.32
F2 P00734 1/20 0.32
F10 P00742 1/20 0.32
PRSS1 P07477 1/20 0.32
PRKDC P78527 3/20 0.31
ALDH1A1 P00352 2/20 0.30
HPGD P15428 2/20 0.30
HSD17B10 Q99714 2/20 0.30
HTT P42858 2/20 0.30
MAPT P10636 2/20 0.30
ALOX15 P16050 1/20 0.30
PDE5A O76074 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24825891 0.97 CYP1A1 (0.33) KDM4EATML3MBTL1CYP1A1CYP1B1
SCHEMBL24825063 0.94 KDM4E (0.32) KDM4EATML3MBTL1CYP1A1CYP1B1
SCHEMBL24826761 0.93 KDM4E (0.37) KDM4EATML3MBTL1CYP1A1CYP1B1
SCHEMBL24827008 0.93 CYP1A1 (0.34) KDM4EATML3MBTL1CYP1A1CYP1B1
SCHEMBL24825788 0.93 KDM4E (0.33) KDM4EATML3MBTL1F2F10
SCHEMBL24825553 0.93 SIRT2 (0.34) KDM4EATML3MBTL1CYP1A1CYP1B1
SCHEMBL24825776 0.91 CYP1A1 (0.32) KDM4EATML3MBTL1CYP1A1CYP1B1
SCHEMBL24825881 0.90 KDM4E (0.33) KDM4EATML3MBTL1CYP1A1CYP1B1
SCHEMBL24826618 0.90 KDM4E (0.33) KDM4EATML3MBTL1F2F10
SCHEMBL24826765 0.90 KDM4E (0.33) KDM4EATML3MBTL1CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329025-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-10-12 US disclosed
US-20230329025-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-10-12 US disclosed
US-20220416174-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-12-29 US disclosed