Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | PRKCI | P41743 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.60 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.60 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482865 | 1.00 | JAK2 (1.00) | JAK2POLBPRKCIALDH1A1HTT | |
| SCHEMBL30628149 | 1.00 | JAK2 (1.00) | JAK2POLBPRKCIALDH1A1HTT | |
| SCHEMBL2482872 | 1.00 | JAK2 (1.00) | JAK2POLBPRKCIALDH1A1HTT | |
| SCHEMBL13339099 | 0.94 | JAK2 (0.88) | JAK2POLBPRKCIALDH1A1HTT | |
| SCHEMBL2486223 | 0.94 | JAK2 (0.88) | JAK2POLBPRKCIALDH1A1HTT | |
| SCHEMBL2486227 | 0.94 | JAK2 (0.88) | JAK2POLBPRKCIALDH1A1HTT | |
| SCHEMBL15999194 | 0.92 | JAK2 (0.85) | JAK2POLBPRKCIALDH1A1HTT | |
| SCHEMBL2485261 | 0.88 | JAK2 (0.78) | JAK2POLBPRKCIALDH1A1HTT | |
| SCHEMBL2485257 | 0.88 | JAK2 (0.78) | JAK2POLBPRKCIALDH1A1HTT | |
| SCHEMBL2485483 | 0.88 | JAK2 (0.78) | JAK2POLBPRKCIALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365429-A1 | PRODUCTION OF VIRUS-RECEPTIVE PLURIPOTENT STEM CELL (PSC)-DERIVED HEPATOCYTES | FUJIFILM Cellular Dynamics, Inc. (US) | 2018-08-29 | — | — | EP | claimed |
| WO-2017070145-A1 | PRODUCTION OF VIRUS-RECEPTIVE PLURIPOTENT STEM CELL (PSC)-DERIVED HEPATOCYTES | CELLULAR DYNAMICS INTERNATIONAL, INC. (US) | 2017-04-27 | — | — | WO | claimed |
| US-9133039-B2 | Kinase inhibitor compounds | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-09-15 | — | — | US | claimed |
| US-20140248634-A1 | VIMENTIN AS A BIOMARKER FOR THE PROGRESSION OF MYELOPROLIFERATIVE NEOPLASMS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2014-09-04 | — | — | US | claimed |
| US-20140193518-A1 | KINASE INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-07-10 | — | — | US | claimed |
| WO-2013019655-A2 | VIMENTIN AS A BIOMARKER FOR THE PROGRESSION OF MYELOPROLIFERATIVE NEOPLASMS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2013-02-07 | — | — | WO | claimed |
| US-8367078-B2 | Kinase inhibitor compounds | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-02-05 | — | — | US | claimed |
| US-20110301159-A1 | KINASE INHIBITOR COMPOUNDS | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-12-08 | — | — | US | claimed |
| EP-2376425-A2 | KINASE INHIBITOR COMPOUNDS | University of Florida Research Foundation, Inc. (US) | 2011-10-19 | — | — | EP | claimed |
| US-20100278933-A1 | KINASE INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC (US) | 2010-11-04 | — | — | US | claimed |
| WO-2010068710-A2 | KINASE INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-06-17 | — | — | WO | claimed |
| WO-2008153900-A1 | KINASE INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2008-12-18 | — | — | WO | claimed |
| US-20240010989-A1 | MEDIUM FOR CULTURING AND EXPANDING NEPHRON PROGENITOR CELLS, METHOD FOR CULTURING AND EXPANDING NEPHRON PROGENITOR CELLS, AND METHOD FOR PRODUCING RENAL ORGANOIDS | KYOTO UNIVERSITY (JP) | 2024-01-11 | — | — | US | disclosed |
| EP-4276172-A1 | MEDIUM FOR CULTURING AND EXPANDING NEPHRON PROGENITOR CELLS, METHOD FOR CULTURING AND EXPANDING NEPHRON PROGENITOR CELLS, AND METHOD FOR PRODUCING RENAL ORGANOIDS | Kyoto University (JP) | 2023-11-15 | — | — | EP | disclosed |
| CN-116802276-A | Culture medium for expansion culture of kidney progenitor cells, method for expansion culture of kidney progenitor cells, and method for producing kidney organoids | 国立大学法人京都大学 | 2023-09-22 | — | — | CN | disclosed |
| WO-2022149615-A1 | CULTURE MEDIUM FOR EXPANSION CULTURE OF NEPHRON PROGENITOR CELL, METHOD FOR PERFORMING EXPANSION CULTURE OF NEPHRON PROGENITOR CELL, AND METHOD FOR PRODUCING KIDNEY ORGANOID | 国立大学法人京都大学 | 2022-07-14 | — | — | WO | disclosed |
| EP-2376425-A2 | KINASE INHIBITOR COMPOUNDS | University of Florida Research Foundation, Inc. (US) | 2011-10-19 | — | — | EP | disclosed |
| US-20100278933-A1 | KINASE INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC (US) | 2010-11-04 | — | — | US | disclosed |
| WO-2010068710-A2 | KINASE INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-06-17 | — | — | WO | disclosed |
| WO-2008153900-A1 | KINASE INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278933-A1 | KINASE INHIBITOR COMPOUNDS | MAP3K1, MAP3K2, MAP3K6 | JAK2 55/4885POLB 1732/4885PRKCI 50/4885 |
| US-20140193518-A1 | KINASE INHIBITOR COMPOUNDS | MAP3K1, MAP3K2, MAP3K6 | JAK2 55/4885POLB 1732/4885PRKCI 50/4885 |
| US-20110301159-A1 | KINASE INHIBITOR COMPOUNDS | JAK2, JAK1, JAK3 | JAK2 1/4885POLB 1317/4885PRKCI 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.