SCHEMBL2482880

SCHEMBL2482880

CN(C)CCCNc1ccc(N)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.59
BRCA1 P38398 1/20 0.59
HIF1A Q16665 1/20 0.59
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
POLB P06746 5/20 0.50
MAPT P10636 4/20 0.50
TOP2B Q02880 3/20 0.50
BLM P54132 3/20 0.50
ALDH1A1 P00352 3/20 0.50
ADORA2A P29274 3/20 0.50
MAPK1 P28482 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
HTT P42858 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
CSNK1A1 P48729 2/20 0.50
CSNK1D P48730 2/20 0.50
CSNK1G1 Q9HCP0 2/20 0.50
EGFR P00533 1/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18984755 0.92 SMN1; SMN2 (0.67) SMN1; SMN2BRCA1HIF1AMEN1KMT2A
SCHEMBL30818304 0.92 SMN1; SMN2 (0.67) SMN1; SMN2BRCA1HIF1AMEN1KMT2A
SCHEMBL13067655 0.89 SMN1; SMN2 (0.48) SMN1; SMN2BRCA1HIF1AMEN1KMT2A
SCHEMBL18984696 0.88 SMN1; SMN2 (0.55) SMN1; SMN2BRCA1HIF1AMEN1KMT2A
SCHEMBL10814026 0.88 SMN1; SMN2 (0.52) SMN1; SMN2BRCA1HIF1AMEN1KMT2A
SCHEMBL13068244 0.88 SMN1; SMN2 (0.47) SMN1; SMN2BRCA1HIF1AMEN1KMT2A
SCHEMBL6812028 0.86 SMN1; SMN2 (0.62) SMN1; SMN2BRCA1HIF1AMEN1KMT2A
Hydrochloric Acid SCHEMBL4872203 0.85 SMN1; SMN2 (0.60) SMN1; SMN2BRCA1HIF1AMEN1KMT2A
SCHEMBL11645881 0.85 ADORA2A (0.54) SMN1; SMN2BRCA1HIF1AMEN1KMT2A
SCHEMBL10046650 0.84 SMN1; SMN2 (0.73) SMN1; SMN2BRCA1HIF1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2238205-B1 BLUE POLYMERIC HAIR DYES BASF SE (DE) 2018-06-27 EP disclosed
CN-101939386-B Blue polymeric hair dyes BASF SE 2014-06-25 CN disclosed
EP-2376580-B1 POLYMERIC HAIR DYES BASF SE (DE) 2013-08-14 EP disclosed
EP-2376580-B1 POLYMERIC HAIR DYES BASF SE (DE) 2013-08-14 EP disclosed
EP-1937780-B1 MIXTURE OF SULFIDE DYES BASF SE (DE) 2013-02-13 EP disclosed
EP-1937780-B1 MIXTURE OF SULFIDE DYES BASF SE (DE) 2013-02-13 EP disclosed
CN-101326246-B Mixture of sulfide dyes CIBA SC HOLDING AG 2012-09-05 CN disclosed
US-8221508-B2 Polymeric hair dyes BASF SE (DE) 2012-07-17 US disclosed
US-8221508-B2 Polymeric hair dyes BASF SE (DE) 2012-07-17 US disclosed
US-8221508-B2 Polymeric hair dyes BASF SE (DE) 2012-07-17 US disclosed
CN-101326246-A Mixture of sulfide dyes CIBA SC HOLDING AG (CH) 2008-12-17 CN disclosed
EP-1937780-A2 MIXTURE OF SULFIDE DYES Ciba Holding Inc. (CH) 2008-07-02 EP disclosed
CN-101208392-A Sulfide dyes CIBA SC HOLDING AG (CH) 2008-06-25 CN disclosed
EP-1893694-A2 SULFIDE DYES CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2008-03-05 EP disclosed
WO-2006136516-A2 SULFIDE DYES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-12-28 WO disclosed
WO-2006136617-A2 MIXTURE OF SULFIDE DYES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-12-28 WO disclosed
US-4676803-A Reactive azo dyestuffs, free from anionic groups and containing a basic group and halogenotriazinyl radical and useful for dyeing cellulose/polyester BAYER AKTIENGESELLSCHAFT (DE) 1987-06-30 US disclosed
EP-0022209-B1 FLUOR-TRIAZINE DYESTUFFS AND THEIR USE IN DYEING CELLULOSIC FIBROUS MATERIALS BAYER AG (DE) 1985-04-17 EP disclosed
US-4503224-A FIBER-REACTIVE, COTTON-POLYESTER BLENDS BAYER AKTIENGESELLSCHAFT (DE) 1985-03-05 US disclosed
EP-0022209-A2 Fluor-triazine dyestuffs and their use in dyeing cellulosic fibrous materials BAYER AG (DE) 1981-01-14 EP disclosed