Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17812940 | 1.00 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP2C19 | |
| SCHEMBL6998193 | 1.00 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP2C19 | |
| SCHEMBL715774 | 1.00 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP2C19 | |
| SCHEMBL16857497 | 1.00 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP2C19 | |
| SCHEMBL19566139 | 0.87 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP2C19 | |
| SCHEMBL17812928 | 0.87 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP2C19 | |
| SCHEMBL16187270 | 0.87 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP2C19 | |
| SCHEMBL715773 | 0.87 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP2C19 | |
| SCHEMBL13066371 | 0.87 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP2C19 | |
| SCHEMBL16857337 | 0.86 | CHRM2 (0.44) | CHRM2CHRM1CHRM3HSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4112616-A1 | RAD51 INHIBITORS | Cyteir Therapeutics, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |