Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.80 |
| ▸ | GRM1 | Q13255 | 19/20 | 0.80 |
| ▸ | HTR2B | P41595 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8006252 | 0.90 | GRM5 (0.82) | GRM5GRM1HTR2B | |
| Hydrochloric Acid SCHEMBL906758 | 0.89 | GRM5 (0.83) | GRM5GRM1HTR2B | |
| SCHEMBL1635768 | 0.89 | GRM5 (1.00) | GRM5GRM1HTR2B | |
| Hydrochloric Acid SCHEMBL1636466 | 0.88 | GRM5 (1.00) | GRM5GRM1HTR2B | |
| SCHEMBL2483346 | 0.80 | GRM5 (0.67) | GRM5GRM1HTR2B | |
| Hydrochloric Acid SCHEMBL4117859 | 0.79 | GRM5 (0.68) | GRM5GRM1HTR2B | |
| Hydrochloric Acid SCHEMBL2486027 | 0.79 | GRM5 (1.00) | GRM5GRM1HTR2B | |
| SCHEMBL2483350 | 0.79 | GRM5 (0.62) | GRM5GRM1HTR2B | |
| Hydrochloric Acid SCHEMBL4117863 | 0.78 | GRM5 (0.63) | GRM5GRM1HTR2B | |
| Hydrochloric Acid SCHEMBL2482885 | 0.77 | GRM5 (1.00) | GRM5GRM1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276759-B1 | 3-INDAZOLYL-4-PYRIDYLISOTHIAZOLES | LILLY CO ELI (US) | 2011-10-19 | — | — | EP | claimed |