Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 18/20 | 0.77 |
| ▸ | WNT3A | P56704 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22758546 | 0.91 | CTPS1 (0.62) | CTPS1 | |
| SCHEMBL22758540 | 0.89 | CTPS1 (0.60) | CTPS1 | |
| SCHEMBL24832429 | 0.87 | CTPS1 (0.70) | CTPS1 | |
| SCHEMBL21381539 | 0.87 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL30518343 | 0.87 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL21381414 | 0.86 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL30591212 | 0.86 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL30882875 | 0.86 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL24832470 | 0.80 | CTPS1 (0.60) | CTPS1 | |
| SCHEMBL21381550 | 0.80 | CTPS1 (1.00) | CTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870574-B1 | AMINOPYRIMIDINE/PYRAZINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S A S (FR) | 2023-01-04 | — | — | EP | disclosed |