Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21392129 | 0.89 | CTPS1 (0.73) | CTPS1 | |
| SCHEMBL22924895 | 0.87 | CTPS1 (0.68) | CTPS1 | |
| SCHEMBL24832441 | 0.82 | CTPS1 (0.68) | CTPS1 | |
| SCHEMBL30518355 | 0.81 | CTPS1 (0.69) | CTPS1 | |
| SCHEMBL21381410 | 0.81 | CTPS1 (0.69) | CTPS1 | |
| SCHEMBL22749299 | 0.81 | CTPS1 (0.71) | CTPS1 | |
| SCHEMBL29142077 | 0.80 | CTPS1 (0.70) | CTPS1 | |
| SCHEMBL22758553 | 0.79 | CTPS1 (0.64) | CTPS1 | |
| SCHEMBL24832438 | 0.79 | CTPS1 (0.58) | CTPS1 | |
| SCHEMBL21381421 | 0.79 | CTPS1 (0.86) | CTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870574-B1 | AMINOPYRIMIDINE/PYRAZINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S A S (FR) | 2023-01-04 | — | — | EP | disclosed |