SCHEMBL24833766

SCHEMBL24833766

O=C=NCc1ccc(CN=O)cc1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MIF P14174 4/20 0.39
TRPA1 O75762 2/20 0.39
CYP3A4 P08684 2/20 0.37
TSHR P16473 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21089 0.90 MIF (0.44) MIFTRPA1CYP3A4TSHRALDH1A1
SCHEMBL22471901 0.87 MIF (0.43) MIFTRPA1CYP3A4TSHRALDH1A1
Water SCHEMBL14972874 0.87 MIF (0.43) MIFTRPA1CYP3A4TSHRALDH1A1
Water SCHEMBL29040332 0.87 MIF (0.43) MIFTRPA1CYP3A4TSHRALDH1A1
SCHEMBL5466297 0.83 CYP3A4 (0.54) MIFTRPA1CYP3A4TSHRALDH1A1
Cyclohexane SCHEMBL28302863 0.83 MIF (0.40) MIFTRPA1CYP3A4TSHRALDH1A1
SCHEMBL31094964 0.83 MIF (0.40) MIFTRPA1CYP3A4TSHRALDH1A1
SCHEMBL19976123 0.83 MIF (0.42) MIFTRPA1CYP3A4ALDH1A1HPGD
SCHEMBL12026106 0.82 MIF (0.33) MIFTRPA1CYP3A4TSHRALDH1A1
SCHEMBL436823 0.81 IDO1 (0.42) MIFTRPA1CYP3A4TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023274492-A1 CATALYTIC SYNTHESIS OF FREE ISOCYANATES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-01-05 WO disclosed