Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30169703 | 1.00 | CYP2C19 (0.60) | CYP2C19CYP1A2CYP2C9CYP3A4L3MBTL1 | |
| SCHEMBL24076900 | 0.84 | CYP1A2 (0.77) | CYP2C19CYP1A2CYP2C9CYP3A4L3MBTL1 | |
| SCHEMBL24834483 | 0.81 | CYP2C19 (0.54) | CYP2C19CYP1A2CYP2C9CYP3A4L3MBTL1 | |
| SCHEMBL24834481 | 0.79 | CYP2C19 (0.52) | CYP2C19CYP1A2CYP2C9CYP3A4L3MBTL1 | |
| SCHEMBL30169756 | 0.78 | CYP2C19 (0.51) | CYP2C19CYP1A2CYP2C9CYP3A4L3MBTL1 | |
| SCHEMBL24834482 | 0.77 | CYP2C19 (0.49) | CYP2C19CYP1A2CYP2C9CYP3A4L3MBTL1 | |
| SCHEMBL24076243 | 0.76 | CYP2C19 (0.62) | CYP2C19CYP1A2CYP2C9CYP3A4L3MBTL1 | |
| SCHEMBL24076919 | 0.75 | CYP2C19 (0.64) | CYP2C19CYP1A2CYP2C9CYP3A4L3MBTL1 | |
| SCHEMBL1638662 | 0.75 | CYP2C19 (0.49) | CYP2C19CYP1A2CYP2C9CYP3A4L3MBTL1 | |
| SCHEMBL1639394 | 0.74 | MEN1 (0.53) | CYP2C19CYP1A2CYP2C9CYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023275230-A1 | 5-OXO-PYRIDO[2,3-D]PYRIDAZIN-6(5H)-YL ACETAMIDES | JANSSEN PHARMACEUTICA NV (BE) | 2023-01-05 | — | — | WO | disclosed |