SCHEMBL24834873

SCHEMBL24834873

O=C(NC1CCCC(NC(=O)c2ccccc2)C1)c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 10/20 0.75
NPSR1 Q6W5P4 1/20 0.61
NPC1 O15118 3/20 0.59
RAB9A P51151 3/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
ALDH1A1 P00352 1/20 0.58
LMNA P02545 1/20 0.58
HTT P42858 1/20 0.58
HPGD P15428 1/20 0.57
BTK Q06187 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17627163 0.92 NPC1 (0.68) GRM5NPC1RAB9AMEN1KMT2A
SCHEMBL2316588 0.92 NPC1 (0.68) GRM5NPSR1NPC1RAB9AMEN1
SCHEMBL161227 0.89 NPC1 (0.72) GRM5NPSR1NPC1RAB9AMEN1
SCHEMBL17407656 0.89 GRM5 (0.62) GRM5NPSR1NPC1RAB9AMEN1
SCHEMBL23839838 0.89 GRM5 (0.62) GRM5NPSR1NPC1RAB9AMEN1
SCHEMBL13012748 0.89 GRM5 (0.62) GRM5NPSR1NPC1RAB9AMEN1
SCHEMBL24632311 0.89 GRM5 (0.62) GRM5NPSR1NPC1RAB9AMEN1
SCHEMBL9294911 0.89 GRM5 (0.62) GRM5NPSR1NPC1RAB9AMEN1
SCHEMBL23573476 0.87 NPC1 (0.62) GRM5NPSR1NPC1RAB9AMEN1
SCHEMBL23573218 0.87 NPC1 (0.62) GRM5NPSR1NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277593-A1 NOVEL COMPOUND FOR CAPPING LAYER, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 동진쎄미켐 2023-01-05 WO disclosed