Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.59 |
| ▸ | CDK2 | P24941 | 4/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.54 |
| ▸ | PDE8A | O60658 | 4/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3441256 | 0.87 | CDK2 (0.71) | CDK1CDK2CCNB1CCNE1PDE8A | |
| SCHEMBL24434593 | 0.86 | CDK1 (0.61) | CDK1CDK2CCNB1CCNE1PDE8A | |
| SCHEMBL28083712 | 0.84 | CDK1 (0.76) | CDK1CDK2CCNB1CCNE1PDE2A | |
| SCHEMBL27897027 | 0.84 | CDK2 (0.44) | CDK1CDK2CCNB1CCNE1ADORA3 | |
| SCHEMBL23619350 | 0.82 | CDK1 (0.56) | CDK1CDK2CCNB1CCNE1PDE8A | |
| SCHEMBL22402774 | 0.82 | ADORA2A (0.62) | CDK1CDK2CCNB1CCNE1PDE8A | |
| SCHEMBL11258114 | 0.80 | CDK1 (0.51) | CDK1CDK2CCNB1CCNE1PDE8A | |
| SCHEMBL26349114 | 0.80 | CDK1 (0.58) | CDK1CDK2CCNB1CCNE1PDE8A | |
| SCHEMBL27748107 | 0.80 | CDK1 (0.54) | CDK1CDK2CCNB1CCNE1PDE8A | |
| SCHEMBL23867144 | 0.79 | CDK1 (0.56) | CDK1CDK2CCNB1CCNE1PDE8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002437-A1 | ECTONUCLEOTIDASE INHIBITORS AND METHODS OF USE THEREOF | ANTENGENE THERAPEUTICS LIMITED (CN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002437-A1 | ECTONUCLEOTIDASE INHIBITORS AND METHODS OF USE THEREOF | NT5E, ENTPD5, NT5C2 | CDK1 2642/4885CDK2 2444/4885CCNB1 3929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.