⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24836101 | 0.85 | — | — | |
| SCHEMBL19286527 | 0.75 | — | — | |
| SCHEMBL22142162 | 0.75 | — | — | |
| SCHEMBL22142370 | 0.75 | — | — | |
| SCHEMBL24835768 | 0.70 | — | — | |
| SCHEMBL24480761 | 0.68 | — | — | |
| SCHEMBL27013737 | 0.68 | GLA (0.37) | — | |
| SCHEMBL292390 | 0.67 | — | — | |
| SCHEMBL17946240 | 0.66 | MGAM (0.36) | — | |
| SCHEMBL20124488 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002390-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | AMGEN INC. | 2023-01-05 | — | — | US | disclosed |