⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300783 | 0.74 | — | — | |
| Water SCHEMBL28901069 | 0.72 | — | — | |
| SCHEMBL25839610 | 0.70 | — | — | |
| SCHEMBL28199288 | 0.69 | — | — | |
| SCHEMBL26779882 | 0.68 | — | — | |
| SCHEMBL25759165 | 0.66 | PIK3CD (0.31) | — | |
| SCHEMBL14877487 | 0.66 | — | — | |
| SCHEMBL21275728 | 0.66 | PIK3CD (0.31) | — | |
| SCHEMBL25758955 | 0.66 | PIK3CD (0.31) | — | |
| SCHEMBL25758944 | 0.66 | PIK3CD (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002390-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | AMGEN INC. | 2023-01-05 | — | — | US | disclosed |