Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483704 | 1.00 | FNTA (0.40) | FNTAFNTBSCN8AKCNH2OPRD1 | |
| SCHEMBL2180125 | 0.78 | BCHE (0.48) | OPRM1 | |
| SCHEMBL15012084 | 0.78 | BCHE (0.48) | OPRM1 | |
| SCHEMBL15012085 | 0.78 | BCHE (0.48) | OPRM1 | |
| SCHEMBL15012081 | 0.78 | BCHE (0.48) | OPRM1 | |
| SCHEMBL15012080 | 0.78 | BCHE (0.48) | OPRM1 | |
| SCHEMBL2779242 | 0.74 | FNTA (0.41) | FNTAFNTBSCN8AKCNH2OPRD1 | |
| SCHEMBL2779240 | 0.74 | FNTA (0.41) | FNTAFNTBSCN8AKCNH2OPRD1 | |
| SCHEMBL1955506 | 0.73 | JAK2 (0.40) | FNTAFNTBSCN8AKCNH2SCN9A | |
| SCHEMBL27851523 | 0.68 | KCNH2 (0.38) | FNTAFNTBSCN8AKCNH2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9303025-B2 | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBVIE INC. (US) | 2016-04-05 | — | — | US | disclosed |
| EP-2376197-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2011-10-19 | — | — | EP | disclosed |