Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2517350 | 0.81 | KMT2A (0.73) | KMT2APARP10GLAALDH1A1MAPT | |
| SCHEMBL103890 | 0.79 | KMT2A (0.70) | KMT2APARP10GLAALDH1A1MAPT | |
| SCHEMBL503642 | 0.79 | KMT2A (1.00) | KMT2APARP10GLAALDH1A1MAPT | |
| SCHEMBL31343186 | 0.78 | KMT2A (0.68) | KMT2APARP10GLAALDH1A1MAPT | |
| SCHEMBL10121188 | 0.78 | KMT2A (0.68) | KMT2APARP10GLAALDH1A1MAPT | |
| SCHEMBL2102012 | 0.78 | PARP10 (1.00) | KMT2APARP10GLAALDH1A1MAPT | |
| SCHEMBL8679376 | 0.78 | KMT2A (0.68) | KMT2APARP10GLAALDH1A1MAPT | |
| SCHEMBL1029780 | 0.78 | KMT2A (0.68) | KMT2APARP10GLAALDH1A1MAPT | |
| SCHEMBL2890514 | 0.78 | KMT2A (0.68) | KMT2APARP10GLAALDH1A1MAPT | |
| Ethane SCHEMBL27686450 | 0.78 | KMT2A (0.96) | KMT2APARP10GLAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278402-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |