Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 20/20 | 0.90 |
| ▸ | AXL | P30530 | 18/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18580459 | 0.94 | MERTK (1.00) | MERTKAXL | |
| SCHEMBL18580963 | 0.94 | MERTK (1.00) | MERTKAXL | |
| SCHEMBL18580197 | 0.92 | MERTK (1.00) | MERTKAXL | |
| SCHEMBL18580407 | 0.88 | MERTK (1.00) | MERTKAXL | |
| SCHEMBL18580186 | 0.86 | MERTK (1.00) | MERTKAXL | |
| SCHEMBL18580005 | 0.86 | MERTK (1.00) | MERTKAXL | |
| SCHEMBL18579499 | 0.85 | MERTK (1.00) | MERTKAXL | |
| SCHEMBL18579678 | 0.84 | MERTK (1.00) | MERTKAXL | |
| SCHEMBL18579978 | 0.82 | MERTK (1.00) | MERTKAXL | |
| SCHEMBL18580063 | 0.81 | AXL (1.00) | MERTKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | MERTK, ERBB2, SRC | MERTK 1/4885AXL 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.