Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 11/20 | 0.60 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.60 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183341 | 0.98 | LPAR3 (0.58) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL2480132 | 0.98 | LPAR3 (0.63) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL9817809 | 0.96 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL9359795 | 0.96 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL4189844 | 0.96 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL9817835 | 0.96 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL9817795 | 0.96 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL20819185 | 0.93 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL4173775 | 0.93 | CYP3A4 (0.57) | LPAR3LPAR2LPAR1CYP3A4TSHR | |
| SCHEMBL1582975 | 0.90 | LPAR3 (0.67) | LPAR3LPAR2LPAR1CYP3A4LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376543-A1 | PROCESS FOR PREPARING A FUNCTIONALIZED DIENE ELASTOMER, SUCH AS A POLYBUTADIENE | Société de Technologie MICHELIN (FR) | 2011-10-19 | — | — | EP | disclosed |
| EP-2376544-A1 | METHOD FOR PREPARING A FUNCTIONALISED DIENE ELASTOMER SUCH AS POLYBUTADIENE | Société de Technologie MICHELIN (FR) | 2011-10-19 | — | — | EP | disclosed |