⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19242651 | 0.74 | — | — | |
| SCHEMBL23481997 | 0.70 | TP53 (0.33) | — | |
| SCHEMBL18202949 | 0.70 | NPC1 (0.41) | — | |
| SCHEMBL18909345 | 0.68 | — | — | |
| SCHEMBL21673403 | 0.68 | GRIN2D (0.36) | — | |
| SCHEMBL23482020 | 0.68 | TP53 (0.32) | — | |
| SCHEMBL24820012 | 0.65 | KDM1A (0.35) | — | |
| SCHEMBL23029498 | 0.65 | KDM1A (0.38) | — | |
| SCHEMBL17785551 | 0.64 | — | — | |
| SCHEMBL20715611 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725010-B2 | Polyheterocyclic compounds as METTL3 inhibitors | STORM THERAPEUTICS LIMITED (GB) | 2023-08-15 | — | — | US | disclosed |
| US-20230002378-A1 | POLYHETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS | STORM THERAPEUTICS LIMITED (GB) | 2023-01-05 | — | — | US | disclosed |