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SCHEMBL24844276

SCHEMBL24844276

c1ccc(-c2nc(-c3cccc4c3Sc3ccccc3C43c4ccccc4-c4ccccc43)c3ccccc3n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ ATM Q13315 2/20 0.41
▸ PDE5A O76074 6/20 0.34
▸ ABCG2 Q9UNQ0 4/20 0.34
▸ WHR1 P49842 1/20 0.34
▸ ACP1 P24666 5/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ GBA1 P04062 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23814542 0.92 MEN1 (0.47) MEN1KMT2AATMPDE5AABCG2
SCHEMBL23546839 0.87 ATM (0.34) MEN1KMT2AATM
SCHEMBL21151502 0.87 MEN1 (0.42) MEN1KMT2AATMPDE5AABCG2
SCHEMBL24139234 0.86 MEN1 (0.41) MEN1KMT2AATMPDE5AABCG2
SCHEMBL21151979 0.86 MEN1 (0.41) MEN1KMT2AATMPDE5AABCG2
SCHEMBL21151562 0.85 MEN1 (0.43) MEN1KMT2AATMPDE5AABCG2
SCHEMBL21151254 0.84 MEN1 (0.42) MEN1KMT2AATMPDE5AABCG2
SCHEMBL21391948 0.84 TSHR (0.36) MEN1KMT2AATML3MBTL1TDP1
SCHEMBL24182879 0.83 MEN1 (0.43) MEN1KMT2AATMPDE5AWHR1
SCHEMBL24648355 0.83 MEN1 (0.46) MEN1KMT2AATMPDE5AABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230006161-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-05 — — US disclosed