Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24844838 | 0.86 | KMT2A (0.45) | KMT2AKDM4ESMN1; SMN2FDPSCA12 | |
| SCHEMBL1411068 | 0.85 | CA12 (0.48) | KDM4EFDPSCA12CA1CA2 | |
| SCHEMBL9944613 | 0.82 | KDM4E (0.45) | KMT2AKDM4ESMN1; SMN2FDPSMEN1 | |
| SCHEMBL1410986 | 0.80 | EGFR (0.50) | KMT2AKDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL1410982 | 0.80 | EGFR (0.50) | KMT2AKDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL19079040 | 0.79 | CA12 (0.59) | KMT2AKDM4ESMN1; SMN2FDPSCA12 | |
| SCHEMBL20198841 | 0.79 | CA12 (0.46) | KMT2AKDM4ESMN1; SMN2FDPSCA12 | |
| SCHEMBL24844759 | 0.78 | BACE1 (0.40) | KMT2AKDM4ESMN1; SMN2FDPSCA12 | |
| SCHEMBL7911789 | 0.78 | CA12 (0.68) | KMT2AKDM4ESMN1; SMN2FDPSCA12 | |
| SCHEMBL1410815 | 0.78 | CA12 (0.68) | KMT2AKDM4ESMN1; SMN2FDPSCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274257-A1 | IMIDAZOLE COMPOUND, AND INTERMEDIATE AND APPLICATION THEREOF | 诸葛国琴 | 2023-01-05 | — | — | WO | disclosed |