Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.46 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.46 |
| ▸ | ITK | Q08881 | 2/20 | 0.45 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.44 |
| ▸ | CLK2 | P49760 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | MST1R | Q04912 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30163798 | 0.92 | EHMT2 (0.48) | OPRK1EHMT2MAP3K7ITKEHMT1 | |
| SCHEMBL29154814 | 0.92 | EHMT2 (0.48) | OPRK1EHMT2MAP3K7ITKEHMT1 | |
| SCHEMBL30163779 | 0.87 | STING1 (0.48) | OPRK1EHMT2MAP3K7ITKIRAK4 | |
| SCHEMBL30163703 | 0.84 | EHMT2 (0.57) | OPRK1EHMT2MAP3K7ITKEHMT1 | |
| SCHEMBL24845827 | 0.84 | EHMT2 (0.57) | OPRK1EHMT2MAP3K7ITKEHMT1 | |
| Hydrochloric Acid SCHEMBL30163808 | 0.83 | EHMT2 (0.56) | OPRK1EHMT2MAP3K7ITKEHMT1 | |
| SCHEMBL24845161 | 0.82 | MAP3K7 (0.41) | OPRK1EHMT2MAP3K7ITKEHMT1 | |
| SCHEMBL30163826 | 0.82 | MAP3K7 (0.41) | OPRK1EHMT2MAP3K7ITKEHMT1 | |
| SCHEMBL24845520 | 0.82 | MAP3K7 (0.64) | OPRK1EHMT2MAP3K7ITKEHMT1 | |
| SCHEMBL24845491 | 0.82 | MAP3K7 (0.64) | OPRK1EHMT2MAP3K7ITKEHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023275199-A1 | MACROCYCLIC TAK1 INHIBITORS | AQILION AB (SE) | 2023-01-05 | — | — | WO | disclosed |