SCHEMBL24846

SCHEMBL24846

[CH2][NH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8434 0.67
SCHEMBL24845 0.67
SCHEMBL8585535 0.67
Charcoal, Activated SCHEMBL8196903 0.58
Iodide SCHEMBL6028354 0.58
SCHEMBL7642788 0.58
Hydrochloric Acid SCHEMBL1476890 0.58
SCHEMBL621867 0.58
SCHEMBL20477172 0.58
Hydrochloric Acid SCHEMBL4432819 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14433 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113924492-B Detection of microbial endotoxin in oral samples using an aptamer 宝洁公司 2024-07-16 CN claimed
CN-118355123-A Aptamer for personal healthcare applications 宝洁公司 2024-07-16 CN claimed
CN-118339295-A Aptamer for personal healthcare applications 宝洁公司 2024-07-12 CN claimed
US-11946050-B2 Polynucleotide compositions and methods for gene expression regulations APTAH BIO, INC. (US) 2024-04-02 US claimed
WO-2023220744-A2 SINGLE-STRANDED LOOP OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2023-11-16 WO claimed
WO-2023152371-A1 GUIDE OLIGONUCLEOTIDES FOR NUCLEIC ACID EDITING IN THE TREATMENT OF HYPERCHOLESTEROLEMIA PROQR THERAPEUTICS II B.V. (NL) 2023-08-17 WO claimed
US-20230257745-A1 Circular siRNAs BANK OF AMERICA, N.A. 2023-08-17 US claimed
EP-4183399-A1 METHODS AND MEANS FOR EFFICIENT SKIPPING OF AT LEAST EXON 52 OF THE HUMAN DUCHENNE MUSCULAR DYSTROPHY GENE Academisch Ziekenhuis Leiden (NL) 2023-05-24 EP claimed
CN-115996729-A Aptamer for personal healthcare applications 宝洁公司 2023-04-21 CN claimed
US-20230039928-A1 Antisense oligonucleotides for nucleotide deamination in the treatment of Stargardt disease PROQR THERAPEUTICS II B.V. (NL) 2023-02-09 US claimed
EP-0055444-B1 TRISUBSTITUTED PYRIMIDO(5,4-D)PYRIMIDINES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1985-03-20 EP claimed
EP-0042359-B1 PHOSPHONOUS-ACID MONOESTER MONOAMIDE AND ORGANIC POLYMERS STABILIZED THEREWITH CIBA-GEIGY AG (CH) 1984-10-31 EP claimed
EP-0111311-A2 Non-radioactive carriers and radioactive diagnostic agent NIHON MEDI-PHYSICS CO., LTD. (JP) 1984-06-20 EP claimed
US-4451463-A HISTAMINE ANTAGONIST, INHIBITOR OF GASTRIC ACID SECRETION IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-05-29 US claimed
EP-0102893-A1 A novel production of 1-oxacephams SHIONOGI & CO., LTD. (JP) 1984-03-14 EP claimed
EP-0078241-A2 Furanes CIBA-GEIGY AG (CH) 1983-05-04 EP claimed
EP-0078240-A2 Lactones CIBA-GEIGY AG (CH) 1983-05-04 EP claimed
EP-0061318-A2 Guanidinoheterocyclic derivatives as histamine H-2 antagonists IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-09-29 EP claimed
US-RE30731-E Enkephalin analogues Hudson, Derek (GB) 1981-09-01 US claimed
US-4198398-A Enkephalin analogues HUDSON DEREK (GB) 1980-04-15 US claimed