Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 11/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.52 |
| ▸ | PDE2A | O00408 | 1/20 | 0.52 |
| ▸ | PDE6D | O43924 | 1/20 | 0.52 |
| ▸ | PDE8A | O60658 | 1/20 | 0.52 |
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | PDE9A | O76083 | 1/20 | 0.52 |
| ▸ | PDE8B | O95263 | 1/20 | 0.52 |
| ▸ | PDE6A | P16499 | 1/20 | 0.52 |
| ▸ | PDE6G | P18545 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE6B | P35913 | 1/20 | 0.52 |
| ▸ | PDE6C | P51160 | 1/20 | 0.52 |
| ▸ | PDE1A | P54750 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1696030 | 1.00 | CHRM3 (0.58) | CHRM3PDE4BCHRNA7BCHEACHE | |
| SCHEMBL1696027 | 1.00 | CHRM3 (0.58) | CHRM3PDE4BCHRNA7BCHEACHE | |
| SCHEMBL2484367 | 0.93 | CHRM3 (0.54) | CHRM3PDE4BCHRNA7BCHEACHE | |
| SCHEMBL2485738 | 0.93 | CHRM3 (0.54) | CHRM3PDE4BCHRNA7BCHEACHE | |
| SCHEMBL2484634 | 0.93 | CHRM3 (0.54) | CHRM3PDE4BCHRNA7BCHEACHE | |
| SCHEMBL13241002 | 0.93 | CHRM3 (0.53) | CHRM3PDE4BCHRNA7BCHEACHE | |
| SCHEMBL13282720 | 0.93 | CHRM3 (0.57) | CHRM3PDE4BCHRNA7BCHEACHE | |
| SCHEMBL2485740 | 0.93 | CHRM3 (0.54) | CHRM3PDE4BCHRNA7BCHEACHE | |
| SCHEMBL19894808 | 0.93 | CHRM3 (0.55) | CHRM3PDE4BCHRNA7BCHEACHE | |
| SCHEMBL2484366 | 0.93 | CHRM3 (0.54) | CHRM3PDE4BCHRNA7BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376489-A1 | Alkaloid aminoester derivatives and medicinal composition thereof | Chiesi Farmaceutici S.p.A. (IT) | 2011-10-19 | — | — | EP | claimed |
| EP-2376489-A1 | Alkaloid aminoester derivatives and medicinal composition thereof | Chiesi Farmaceutici S.p.A. (IT) | 2011-10-19 | — | — | EP | disclosed |