SCHEMBL2484698

SCHEMBL2484698

C#CCCn1cc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1ONC(C)(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2484701 1.00 CNR2 (1.00) CNR2
SCHEMBL2510556 0.89 CNR2 (1.00) CNR2
SCHEMBL2181888 0.89 CNR2 (0.81) CNR2
SCHEMBL2510558 0.89 CNR2 (1.00) CNR2
SCHEMBL2181896 0.89 CNR2 (0.81) CNR2
SCHEMBL3027807 0.87 CNR2 (0.76) CNR2
SCHEMBL3027805 0.87 CNR2 (0.76) CNR2
SCHEMBL2506124 0.84 CNR2 (1.00) CNR2
SCHEMBL2506121 0.84 CNR2 (1.00) CNR2
SCHEMBL2184940 0.80 CNR2 (1.00) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3026046-A1 THIAZOLES AS CANNABINOID RECEPTOR LIGANDS AbbVie Inc. (US) 2016-06-01 EP claimed
US-8895592-B2 Compounds as cannabinoid receptor ligands ABBVIE INC. (US) 2014-11-25 US claimed
EP-2376462-A1 Thiazoles as cannabinoid receptor ligands Abbott Laboratories (US) 2011-10-19 EP claimed
US-20100216760-A1 NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2010-08-26 US claimed
WO-2010071783-A1 THIAZOLES AS CANNABINOID RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2010-06-24 WO claimed
EP-3026046-A1 THIAZOLES AS CANNABINOID RECEPTOR LIGANDS AbbVie Inc. (US) 2016-06-01 EP disclosed
EP-2376462-B1 THIAZOLES AS CANNABINOID RECEPTOR LIGANDS ABBVIE INC (US) 2015-12-16 EP disclosed
US-8895592-B2 Compounds as cannabinoid receptor ligands ABBVIE INC. (US) 2014-11-25 US disclosed
EP-2376462-A1 Thiazoles as cannabinoid receptor ligands Abbott Laboratories (US) 2011-10-19 EP disclosed
US-20100216760-A1 NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2010-08-26 US disclosed
WO-2010071783-A1 THIAZOLES AS CANNABINOID RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2010-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100216760-A1 NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS CNR1, CNR2, OPRL1 CNR2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.