Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180150 | 1.00 | MEN1 (0.41) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL24847964 | 1.00 | MEN1 (0.41) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL30180067 | 1.00 | MEN1 (0.41) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL31701224 | 0.88 | MEN1 (0.46) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL30180208 | 0.87 | MEN1 (0.38) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL24847116 | 0.87 | MEN1 (0.38) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL30139739 | 0.87 | MEN1 (0.49) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL27208411 | 0.86 | MEN1 (0.45) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL26096472 | 0.86 | PARG (0.38) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL26095887 | 0.86 | PARG (0.38) | MEN1KMT2ALMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278759-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |