Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1719662 | 1.00 | CYP2D6 (0.48) | CYP2D6LMNASPHK1GMNNPOLB | |
| Ammonia Solution, Strong SCHEMBL17695275 | 0.97 | CYP2D6 (0.46) | CYP2D6LMNASPHK1GMNNPOLB | |
| Alcohol SCHEMBL2031858 | 0.92 | CYP2D6 (0.48) | CYP2D6LMNASPHK1GMNNPOLB | |
| Monoethanolamine SCHEMBL2031859 | 0.88 | CYP2D6 (0.45) | CYP2D6LMNASPHK1GMNNPOLB | |
| SCHEMBL7011294 | 0.87 | CYP2D6 (0.59) | CYP2D6LMNASPHK1GMNNPOLB | |
| SCHEMBL1067106 | 0.87 | CYP2D6 (0.48) | CYP2D6LMNASPHK1GMNNPOLB | |
| SCHEMBL14753951 | 0.87 | CYP2D6 (0.48) | CYP2D6LMNASPHK1GMNNPOLB | |
| SCHEMBL14753958 | 0.86 | — | — | |
| SCHEMBL4208579 | 0.86 | — | — | |
| SCHEMBL3369535 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178686-B2 | Process for preparing optically active aminopentane derivative, intermediate and process for preparing intermediate | FUJIMOTO CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| EP-1905760-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINOPENTANE DERIVATIVE, INTERMEDIATE IN THE PROCESS AND PROCESS FOR PRODUCTION OF THE INTERMEDIATE | FUJIMOTO CO LTD (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-20100324300-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE AMINOPENTANE DERIVATIVE, INTERMEDIATE AND PROCESS FOR PREPARING INTERMEDIATE | YONEDA FUMIO | 2010-12-23 | — | — | US | disclosed |
| US-7807840-B2 | Process for preparing optically active aminopentane derivative, intermediate and process for preparing intermediate | FUJIMOTO CO., LTD. (JP) | 2010-10-05 | — | — | US | disclosed |
| US-20090124813-A1 | Process for Preparing Optically Active Aminopentane Derivative, Intermediate and Process for Preparing Intermediate | FUJIMOTO CO., LTD. (JP) | 2009-05-14 | — | — | US | disclosed |
| EP-1905760-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINOPENTANE DERIVATIVE, INTERMEDIATE IN THE PROCESS AND PROCESS FOR PRODUCTION OF THE INTERMEDIATE | Fujimoto Co., Ltd. (JP) | 2008-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124813-A1 | Process for Preparing Optically Active Aminopentane Derivative, Intermediate and Process for Preparing Intermediate | API5, CASP5, BAD | CYP2D6 232/4885LMNA 618/4885SPHK1 1987/4885 |
| US-20100324300-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE AMINOPENTANE DERIVATIVE, INTERMEDIATE AND PROCESS FOR PREPARING INTERMEDIATE | API5, CASP5, BAD | CYP2D6 232/4885LMNA 618/4885SPHK1 1987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.