Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13241016 | 1.00 | CHRM3 (0.58) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL13240846 | 0.94 | CHRM3 (0.51) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL2485023 | 0.90 | CHRM3 (0.56) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL1695646 | 0.90 | CHRM3 (0.56) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL13240822 | 0.90 | CHRM3 (0.56) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL1695649 | 0.90 | CHRM3 (0.56) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL19895072 | 0.88 | CHRM3 (0.55) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL1695924 | 0.87 | CHRM3 (0.58) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL1695927 | 0.87 | CHRM3 (0.58) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL1695933 | 0.86 | CHRM3 (0.62) | CHRM3CHRNA7BCHEACHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376489-A1 | Alkaloid aminoester derivatives and medicinal composition thereof | Chiesi Farmaceutici S.p.A. (IT) | 2011-10-19 | — | — | EP | disclosed |