SCHEMBL24848314

SCHEMBL24848314

CCc1ccc(-c2cc3c(cn2)CCc2c-3[nH]c3c2C(=O)NCC32CC2)cc1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPKAPK2 P49137 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26450034 0.90 MAPKAPK2 (0.81) MAPKAPK2
SCHEMBL1909181 0.88 MAPKAPK2 (0.78) MAPKAPK2
SCHEMBL1909019 0.87 MAPKAPK2 (0.69) MAPKAPK2
SCHEMBL1908992 0.87 MAPKAPK2 (0.69) MAPKAPK2
SCHEMBL24848313 0.87 MAPKAPK2 (0.77) MAPKAPK2
SCHEMBL1909183 0.87 MAPKAPK2 (1.00) MAPKAPK2
SCHEMBL1908973 0.87 MAPKAPK2 (0.79) MAPKAPK2
SCHEMBL13957102 0.86 MAPKAPK2 (0.76) MAPKAPK2
SCHEMBL13081315 0.86 MAPKAPK2 (0.68) MAPKAPK2
SCHEMBL13883927 0.85 MAPKAPK2 (0.74) MAPKAPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023278759-A1 MK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2023-01-05 WO disclosed