Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 20/20 | 0.62 |
| ▸ | MAPK9 | P45984 | 15/20 | 0.62 |
| ▸ | MAPK10 | P53779 | 8/20 | 0.60 |
| ▸ | RPS27 | P42677 | 3/20 | 0.60 |
| ▸ | PRKD2 | Q9BZL6 | 6/20 | 0.59 |
| ▸ | CSF1R | P07333 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.59 |
| ▸ | AKT1 | P31749 | 3/20 | 0.59 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.59 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.59 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.55 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.55 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.55 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.55 |
| ▸ | JUN | P05412 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.54 |
| ▸ | KIT | P10721 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1315428 | 0.94 | MAPK8 (0.56) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL1318078 | 0.89 | MAPK8 (0.60) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL1318316 | 0.86 | MAPK8 (0.59) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL12113589 | 0.82 | MAPK8 (0.55) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL1145113 | 0.82 | MAPK8 (0.64) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| Hydrochloric Acid SCHEMBL1314890 | 0.81 | MAPK8 (0.62) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL12113593 | 0.79 | MAPK8 (0.47) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL13514197 | 0.79 | MAPK8 (0.83) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL13514301 | 0.78 | MAPK8 (0.70) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL13514091 | 0.77 | MAPK8 (0.73) | MAPK8MAPK9MAPK10RPS27PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2375899-A1 | PIPERIDINE-CONTAINING COMPOUNDS AND USE THEREOF | Array Biopharma, Inc. (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010080864-A1 | PIPERIDINE-CONTAINING COMPOUNDS AND USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2010-07-15 | — | — | WO | disclosed |