⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27892844 | 0.80 | CHRNA4 (0.44) | — | |
| SCHEMBL438341 | 0.78 | — | — | |
| SCHEMBL2170860 | 0.78 | — | — | |
| Benzene SCHEMBL28325923 | 0.76 | CHRNA4 (0.46) | — | |
| SCHEMBL22361539 | 0.76 | — | — | |
| SCHEMBL2413529 | 0.76 | — | — | |
| SCHEMBL3114585 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL30596464 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL29156121 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL29290252 | 0.74 | CHRNA4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243177-A1 | sGC STIMULATORS | CYCLERION THERAPEUTICS, INC. | 2025-07-31 | — | — | US | disclosed |
| CN-107021951-B | sGC stimulators | 赛克里翁治疗有限公司 | 2020-10-20 | — | — | CN | disclosed |
| EP-3668845-A1 | HERBICIDALLY ACTIVE 3-PHENYL-5-TRIFLUOROMETHYLISOXAZOLINE-5-CARBOXAMIDES OF CYCLOPENTYLCARBOXYLIC ACIDS AND ESTERS | Bayer Aktiengesellschaft (DE) | 2020-06-24 | — | — | EP | disclosed |
| US-20190345130-A1 | SGC STIMULATORS | CYCLERION THERAPEUTICS, INC. | 2019-11-14 | — | — | US | disclosed |
| US-10189809-B2 | SGC stimulators | IRONWOOD PHARMACEUTICALS, INC. (US) | 2019-01-29 | — | — | US | disclosed |
| CN-108707147-A | A kind of novel tubulin inhibitor and its application in antitumor drug | 桑文军 | 2018-10-26 | — | — | CN | disclosed |
| CN-108658963-A | A kind of antitumor drug acting on tubulin | 桑文军 | 2018-10-16 | — | — | CN | disclosed |
| US-20170305878-A1 | sGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2017-10-26 | — | — | US | disclosed |
| CN-107021951-A | SGC stimulators | 铁木医药有限公司 | 2017-08-08 | — | — | CN | disclosed |
| EP-3173407-A1 | SGC STIMULATORS | Ironwood Pharmaceuticals, Inc. (US) | 2017-05-31 | — | — | EP | disclosed |
| CN-101018770-A | PGD2 receptor antagonists for the treatment of inflammatory diseases | MILLENNIUM PHARM INC (US) | 2007-08-15 | — | — | CN | disclosed |
| US-20060148789-A1 | Novel diazabicyclic aryl derivatives | NEUROSEARCH A/S (DK) | 2006-07-06 | — | — | US | disclosed |
| EP-1599476-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004076453-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2004-09-10 | — | — | WO | disclosed |
| US-20040097499-A1 | Amide, carbamate, and urea derivatives | ARNOLD MACKLIN BRIAN (US) | 2004-05-20 | — | — | US | disclosed |
| US-6617351-B1 | Amide, carbamate, and urea derivatives | ELI LILLY AND COMPANY | 2003-09-09 | — | — | US | disclosed |
| WO-2000006156-A1 | AMIDE, CARBAMATE, AND UREA DERIVATIVES | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976744-A1 | Amide, carbamate, and urea derivatives having glutamate receptor function potentiating activity | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| US-5859008-A | Arylalkyl diazinones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-01-12 | — | — | US | disclosed |
| US-4785012-A | OXAZOLE DERIVATIVES CONTAINING ALCOHOLS OR ESTERS | SYNTEX CORPORATION (US) | 1988-11-15 | — | — | US | disclosed |