Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.34 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL650143 | 0.81 | MAPT (0.41) | MAPTNPSR1TDP1L3MBTL1MAPK1 | |
| SCHEMBL650142 | 0.81 | MAPT (0.41) | MAPTNPSR1TDP1L3MBTL1MAPK1 | |
| SCHEMBL650808 | 0.81 | MAPT (0.43) | MAPTNPSR1TDP1L3MBTL1MAPK1 | |
| SCHEMBL650809 | 0.81 | MAPT (0.43) | MAPTNPSR1TDP1L3MBTL1MAPK1 | |
| SCHEMBL8511177 | 0.80 | MAPT (0.40) | MAPTNPSR1TDP1L3MBTL1MAPK1 | |
| SCHEMBL8511185 | 0.80 | MAPT (0.40) | MAPTNPSR1TDP1L3MBTL1MAPK1 | |
| SCHEMBL247678 | 0.79 | CDC7 (0.45) | MAPTNPSR1TDP1L3MBTL1MAPK1 | |
| SCHEMBL8513536 | 0.79 | CDC7 (0.45) | MAPTNPSR1TDP1L3MBTL1MAPK1 | |
| SCHEMBL10176480 | 0.78 | MAPT (0.41) | MAPTNPSR1TDP1L3MBTL1MAPK1 | |
| SCHEMBL653599 | 0.77 | MAPT (0.40) | MAPTNPSR1TDP1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588478-A1 | AZAINDOLE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2013-05-08 | — | — | EP | claimed |
| WO-2012002568-A1 | AZAINDOLE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2012-01-05 | — | — | WO | claimed |