SCHEMBL2485360

SCHEMBL2485360

O=C1OC(=O)Oc2ccc3c4ccc(Br)c5cccc(c6ccc(c2c63)O1)c54

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.36
CYP1B1 Q16678 12/20 0.36
PARP1 P09874 1/20 0.35
ALDH1A1 P00352 2/20 0.33
POLB P06746 2/20 0.33
RXFP1 Q9HBX9 1/20 0.33
LMNA P02545 2/20 0.32
TP53 P04637 1/20 0.32
THRB P10828 1/20 0.32
TLR9 Q9NR96 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP1A2 P05177 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
PABPC1 P11940 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL297185 0.82 TYMS (0.31) TYMS
SCHEMBL2591498 0.81 TYMS (0.44) TYMSCYP1B1PARP1ALDH1A1POLB
SCHEMBL17555050 0.76 KDM4E (0.40) TYMSALDH1A1KDM4EMAPT
SCHEMBL200283 0.76 TYMS (0.47) TYMSCYP1B1ALDH1A1POLBRXFP1
SCHEMBL29406732 0.75 CYP1A2 (0.45) TYMSCYP1B1PARP1ALDH1A1POLB
SCHEMBL2679177 0.75 CYP1A2 (0.45) TYMSCYP1B1PARP1ALDH1A1POLB
SCHEMBL3575204 0.75 CYP1A2 (0.45) TYMSCYP1B1PARP1ALDH1A1POLB
SCHEMBL29405395 0.75 CYP1A2 (0.45) TYMSCYP1B1PARP1ALDH1A1POLB
SCHEMBL5669943 0.73 TYMS (0.36) TYMS
SCHEMBL4681733 0.72 AHR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1542975-B1 9-CYANO-SUBSTITUTED PERYLENE-3,4-DICARBOXYLIC ACID MONOIMIDES BASF SE (DE) 2016-03-09 EP claimed
EP-1542975-B1 9-CYANO-SUBSTITUTED PERYLENE-3,4-DICARBOXYLIC ACID MONOIMIDES BASF SE (DE) 2016-03-09 EP disclosed
EP-2029573-B1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS BASF SE (DE) 2011-10-26 EP disclosed
EP-2029573-A1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS BASF SE (DE) 2009-03-04 EP disclosed
EP-2008319-A2 LIQUID CRYSTALLINE RYLENE TETRACARBOXYLIC ACID DERIVATIVES AND USE THEREOF BASF SE (DE) 2008-12-31 EP disclosed
WO-2007138051-A1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS BASF SE (DE) 2007-12-06 WO disclosed
WO-2007116001-A2 LIQUID CRYSTALLINE RYLENE TETRACARBOXYLIC ACID DERIVATIVES AND USE THEREOF BASF SE (DE) 2007-10-18 WO disclosed
EP-1542975-A2 9-CYANO-SUBSTITUTED PERYLENE-3,4-DICARBOXYLIC ACID MONOIMIDES BASF AKTIENGESELLSCHAFT (DE) 2005-06-22 EP disclosed
WO-2004029028-A2 9-CYANO-SUBSTITUTED PERYLENE-3,4-DICARBOXYLIC ACID MONOIMIDES AS DYESTUFFS BASF AKTIENGESELLSCHAFT (DE) 2004-04-08 WO disclosed