⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17551253 | 0.91 | — | — | |
| SCHEMBL11058091 | 0.85 | — | — | |
| SCHEMBL172565 | 0.83 | CHRM2 (0.34) | — | |
| SCHEMBL8345303 | 0.82 | — | — | |
| SCHEMBL17172128 | 0.82 | — | — | |
| SCHEMBL8344700 | 0.82 | — | — | |
| SCHEMBL17553594 | 0.82 | — | — | |
| SCHEMBL13346152 | 0.82 | — | — | |
| SCHEMBL18792819 | 0.82 | — | — | |
| SCHEMBL14355432 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002403-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. | 2023-01-05 | — | — | US | disclosed |