Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24854369 | 1.00 | HRH3 (0.31) | HRH3IRAK4 | |
| SCHEMBL24854068 | 1.00 | HRH3 (0.31) | HRH3IRAK4 | |
| SCHEMBL24854370 | 1.00 | HRH3 (0.31) | HRH3IRAK4 | |
| SCHEMBL24854519 | 0.91 | HRH3 (0.34) | HRH3IRAK4 | |
| SCHEMBL24854517 | 0.91 | HRH3 (0.34) | HRH3IRAK4 | |
| SCHEMBL24854073 | 0.91 | HRH3 (0.31) | HRH3 | |
| SCHEMBL24854274 | 0.91 | HRH3 (0.31) | HRH3 | |
| SCHEMBL24854512 | 0.89 | ATM (0.31) | — | |
| SCHEMBL24854829 | 0.89 | ATM (0.34) | IRAK4 | |
| SCHEMBL23588614 | 0.89 | ATM (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002382-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUNDS | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002382-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUNDS | KRAS, NRAS, HRAS | HRH3 2019/4885IRAK4 1415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.