Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9289352 | 0.77 | CHRM2 (0.55) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL9387164 | 0.77 | CHRM2 (0.50) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL96686 | 0.77 | CHRM2 (0.55) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL15500344 | 0.77 | CHRM2 (0.50) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL13907240 | 0.77 | CHRM2 (0.55) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL2739921 | 0.72 | CHRM2 (0.50) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL12395656 | 0.72 | CHRM2 (0.50) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL9094744 | 0.72 | CHRM1 (0.58) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL21361195 | 0.72 | CHRM2 (0.50) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL3743481 | 0.72 | CHRM2 (0.71) | CHRM2CHRM1CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002382-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUNDS | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002382-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUNDS | KRAS, NRAS, HRAS | CHRM2 4863/4885CHRM1 4819/4885CYP2D6 1945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.