⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007666 | 0.76 | — | — | |
| SCHEMBL8173264 | 0.76 | — | — | |
| SCHEMBL20387745 | 0.72 | — | — | |
| SCHEMBL21347980 | 0.72 | — | — | |
| SCHEMBL23055220 | 0.72 | — | — | |
| SCHEMBL18102222 | 0.72 | — | — | |
| SCHEMBL11915748 | 0.69 | — | — | |
| SCHEMBL24297549 | 0.69 | — | — | |
| SCHEMBL22562173 | 0.69 | — | — | |
| SCHEMBL19098977 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740483-B1 | QUINOXALINONE COMPOUNDS, COMPOSITIONS, METHODS, AND KITS FOR INCREASING GENOME EDITING EFFICIENCY | VERTEX PHARMA (US) | 2023-01-11 | — | — | EP | disclosed |