Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 1.00 |
| ▸ | BTK | Q06187 | 7/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18665587 | 1.00 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL18666042 | 1.00 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL29886839 | 1.00 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL18665568 | 0.95 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL18665590 | 0.95 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL20584017 | 0.94 | EGFR (0.97) | EGFRBTK | |
| SCHEMBL18665626 | 0.93 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL31188088 | 0.91 | EGFR (0.84) | EGFRBTK | |
| SCHEMBL18665620 | 0.91 | EGFR (0.84) | EGFRBTK | |
| SCHEMBL18665570 | 0.91 | EGFR (1.00) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4116303-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS BTK INHIBITORS FOR THE TREATMENT OF CANCER | Loxo Oncology, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |