SCHEMBL24862014

SCHEMBL24862014

C=CC(=O)N1CCN(CCCCCn2nc(-c3ccc(O)cc3)c3c(N)ncnc32)CC1

nearest known ligand 0.85

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 18/20 0.85
▸ FGFR2 P21802 17/20 0.85
▸ FGFR3 P22607 14/20 0.85
▸ FGFR4 P22455 13/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24547539 0.92 FGFR1 (1.00) FGFR1FGFR2FGFR3FGFR4
SCHEMBL26165821 0.92 FGFR1 (0.84) FGFR1FGFR2FGFR3FGFR4
SCHEMBL24547567 0.90 FGFR2 (1.00) FGFR1FGFR2FGFR3FGFR4
SCHEMBL24862275 0.89 FGFR1 (0.79) FGFR1FGFR2FGFR3FGFR4
SCHEMBL26165825 0.88 FGFR1 (0.82) FGFR1FGFR2FGFR3FGFR4
SCHEMBL24547587 0.88 FGFR1 (1.00) FGFR1FGFR2FGFR3FGFR4
SCHEMBL24547717 0.88 FGFR1 (1.00) FGFR1FGFR2FGFR3FGFR4
SCHEMBL24547719 0.87 FGFR1 (1.00) FGFR1FGFR2FGFR3FGFR4
SCHEMBL24547705 0.87 FGFR1 (0.76) FGFR1FGFR2FGFR3FGFR4
SCHEMBL24547585 0.86 FGFR1 (1.00) FGFR1FGFR2FGFR3FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4116302-A1 COMPOUND AND PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN PREPARATION OF THERAPEUTIC ANTI-CANCER DRUG Tianjin Jikun Medical Technology Co., Ltd. (CN) 2023-01-11 — — EP disclosed
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