Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 12/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMO | Q99835 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24862886 | 0.91 | CAPN1 (0.57) | CAPN1NPC1RAB9ASMOPOLB | |
| SCHEMBL23355169 | 0.86 | CAPN1 (0.58) | CAPN1ITGB1ITGA4ITGB7 | |
| SCHEMBL19248290 | 0.84 | CAPN1 (0.71) | CAPN1NPC1 | |
| SCHEMBL24862871 | 0.83 | CAPN1 (0.73) | CAPN1 | |
| SCHEMBL24863043 | 0.83 | CAPN1 (0.69) | CAPN1 | |
| SCHEMBL24862869 | 0.83 | CAPN1 (0.69) | CAPN1NPC1RAB9APOLB | |
| SCHEMBL7787032 | 0.82 | CAPN1 (1.00) | CAPN1 | |
| SCHEMBL7786977 | 0.82 | CAPN1 (1.00) | CAPN1 | |
| SCHEMBL7379589 | 0.82 | CAPN1 (1.00) | CAPN1 | |
| SCHEMBL7375338 | 0.82 | CAPN1 (0.67) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102193-B1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | UNIV RUTGERS (US) | 2023-01-11 | — | — | EP | disclosed |