SCHEMBL24864452

CN[C@@H](CCCCNC(=O)CCOCCOCCOCCOCCOCCOCCN(C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1)C(C)C

nearest known ligand 0.35

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	FURIN	P09958	9/20	0.35

▸	SIRT1	Q96EB6	3/20	0.31

▸	SIRT2	Q8IXJ6	2/20	0.31

▸	IL23R	Q5VWK5	3/20	0.31

▸	SIRT5	Q9NXA8	1/20	0.31

▸	FAP	Q12884	1/20	0.30

▸	CTSD	P07339	1/20	0.30

▸	HTT	P42858	1/20	0.30

▸	SIRT3	Q9NTG7	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24864398	1.00	FURIN (0.35)	FURINSIRT1SIRT2IL23RSIRT5
SCHEMBL24864477	0.97	FURIN (0.34)	FURINSIRT2IL23R
SCHEMBL24864406	0.95	FURIN (0.35)	FURINIL23RCTSD
SCHEMBL24864376	0.95	FURIN (0.34)	FURINSIRT1SIRT2SIRT5FAP
SCHEMBL24864648	0.95	FURIN (0.33)	FURINIL23RFAP
SCHEMBL24864529	0.94	FURIN (0.34)	FURINIL23R
SCHEMBL24864375	0.94	FURIN (0.34)	FURINSIRT1SIRT2SIRT5FAP
SCHEMBL24864514	0.94	FURIN (0.35)	FURINIL23RCTSD
SCHEMBL27291540	0.93	FURIN (0.35)	FURINIL23R
SCHEMBL24864391	0.93	FURIN (0.33)	FURINSIRT1SIRT2IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023280227-A2	LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME	PROFOUNDBIO US CO. (US)	2023-01-12	—	—	WO	disclosed