Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1536707 | 0.80 | STING1 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29155906 | 0.80 | STING1 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL18843243 | 0.80 | STING1 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL5735427 | 0.80 | STING1 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL5737163 | 0.80 | STING1 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL25933065 | 0.80 | STING1 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL31524058 | 0.79 | CA12 (0.40) | — | |
| SCHEMBL18059176 | 0.79 | CA12 (0.40) | — | |
| SCHEMBL31524088 | 0.79 | CA12 (0.40) | — | |
| SCHEMBL24864342 | 0.79 | BLM (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |