SCHEMBL24864993

SCHEMBL24864993

O=C(c1c(O)c2cc3sc4ccccc4c3cc2n(-c2ccccc2)c1=O)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 2/20 0.41
HTR3E A5X5Y0 1/20 0.38
HTR3B O95264 1/20 0.38
HTR3A P46098 1/20 0.38
HTR3D Q70Z44 1/20 0.38
HTR3C Q8WXA8 1/20 0.38
KMT2A Q03164 3/20 0.37
CYP1A2 P05177 3/20 0.34
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 3/20 0.34
PMM2 O15305 2/20 0.34
MPI P34949 2/20 0.34
PHOSPHO1 Q8TCT1 2/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
PTPN7 P35236 1/20 0.34
DUSP3 P51452 1/20 0.34
PTPN12 Q05209 1/20 0.34
PTPN22 Q9Y2R2 1/20 0.34
IDE P14735 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24864736 0.86 RECQL (0.41) RECQLHTR3EHTR3BHTR3AHTR3D
SCHEMBL24864738 0.81 RECQL (0.39) RECQLHTR3EHTR3BHTR3AHTR3D
SCHEMBL24864728 0.80 RECQL (0.60) RECQLHTR3EHTR3BHTR3AHTR3D
SCHEMBL30804596 0.80 RECQL (0.60) RECQLHTR3EHTR3BHTR3AHTR3D
SCHEMBL24864741 0.80 RECQL (0.38) RECQLHTR3EHTR3BHTR3AHTR3D
SCHEMBL24864715 0.80 RECQL (0.37) RECQLKMT2ACYP1A2KDM4ECYP2C9
SCHEMBL24864991 0.79 RECQL (0.36) RECQLHTR3EHTR3BHTR3AHTR3D
SCHEMBL30171422 0.79 RECQL (0.36) RECQLHTR3EHTR3BHTR3AHTR3D
Water SCHEMBL30804606 0.78 RECQL (0.57) RECQLHTR3EHTR3BHTR3AHTR3D
SCHEMBL24864964 0.77 RECQL (0.51) RECQLHTR3EHTR3BHTR3AHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023282236-A1 RARE EARTH COMPLEX 東ソー株式会社 2023-01-12 WO disclosed