SCHEMBL24865002

SCHEMBL24865002

O=C(c1c(O)c2c(ccc3sc4ccccc4c32)oc1=O)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
HPGD P15428 4/20 0.36
LMNA P02545 3/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
ALDH1A1 P00352 6/20 0.35
MAPT P10636 5/20 0.34
KDM4E B2RXH2 5/20 0.34
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
POLB P06746 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
HTT P42858 3/20 0.34
DUSP3 P51452 1/20 0.34
BLM P54132 1/20 0.34
PTPN5 P54829 1/20 0.34
PTPN11 Q06124 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24865020 0.85 CA12 (0.36) CA12CA9MAOAMAOBHPGD
SCHEMBL24865003 0.85 ESR2 (0.39) CA12CA9HPGDLMNAESR1
SCHEMBL24865005 0.81 CA12 (0.50) CA12CA9HPGDLMNAALDH1A1
SCHEMBL24865031 0.80 CA12 (0.41) CA12CA9HPGDLMNAESR2
SCHEMBL24865117 0.80 CA12 (0.41) CA12CA9HPGDLMNAESR2
SCHEMBL24864749 0.79 KDM4E (0.47) CA12CA9MAOBHPGDLMNA
SCHEMBL24864745 0.76 CA12 (0.65) CA12CA9HPGDLMNAALDH1A1
SCHEMBL24865006 0.76 CA12 (0.47) CA12CA9HPGDLMNAALDH1A1
SCHEMBL24865008 0.74 HTT (0.40) CA12CA9HPGDLMNAALDH1A1
SCHEMBL24864783 0.74 ESR2 (0.42) CA12CA9HPGDLMNAESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023282236-A1 RARE EARTH COMPLEX 東ソー株式会社 2023-01-12 WO disclosed