Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | BRD1 | O95696 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336132 | 1.00 | BCL6 (0.49) | BCL6SMN1; SMN2GAAPRKDCPIK3CA | |
| SCHEMBL24865177 | 0.90 | BCL6 (0.49) | BCL6SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL31123228 | 0.90 | BCL6 (0.49) | BCL6SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL24865486 | 0.88 | BCL6 (0.47) | BCL6SMN1; SMN2GAAPRKDCPIK3CA | |
| SCHEMBL31123290 | 0.88 | BCL6 (0.47) | BCL6SMN1; SMN2GAAPRKDCPIK3CA | |
| SCHEMBL24865775 | 0.85 | MAPT (0.51) | BCL6SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL31123194 | 0.85 | MAPT (0.51) | BCL6SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL31123303 | 0.82 | BCL6 (0.48) | BCL6SMN1; SMN2GAAPRKDCPIK3CA | |
| SCHEMBL24865777 | 0.82 | BCL6 (0.48) | BCL6SMN1; SMN2GAAPRKDCPIK3CA | |
| SCHEMBL24865299 | 0.81 | BCL6 (0.50) | BCL6SMN1; SMN2GAAPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |