Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | BCL6 | P41182 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | CCND2 | P30279 | 2/20 | 0.34 |
| ▸ | CCND3 | P30281 | 2/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123376 | 1.00 | ERCC1 (0.37) | ERCC1DNASE1FEN1ERCC4SYK | |
| SCHEMBL24865512 | 0.89 | CNR2 (0.35) | ERCC1DNASE1FEN1ERCC4SYK | |
| SCHEMBL24865221 | 0.87 | SMN1; SMN2 (0.43) | ERCC1DNASE1FEN1ERCC4ALOX5 | |
| SCHEMBL24865203 | 0.87 | APP (0.39) | SCN10AALOX5APPEGFRPTGES | |
| SCHEMBL24865742 | 0.83 | MAPT (0.43) | ERCC1DNASE1FEN1ERCC4ALOX5 | |
| SCHEMBL24865749 | 0.81 | BCL6 (0.39) | SYKBCL6CNR2MGLLPTGES | |
| SCHEMBL24865543 | 0.79 | CNR2 (0.37) | SYKBCL6CNR2MGLLJAK2 | |
| SCHEMBL24865678 | 0.79 | BCL6 (0.40) | ERCC1DNASE1FEN1ERCC4SYK | |
| SCHEMBL31123319 | 0.79 | BCL6 (0.40) | ERCC1DNASE1FEN1ERCC4SYK | |
| SCHEMBL24865665 | 0.78 | APP (0.54) | SYKBCL6CNR2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |