⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26635783 | 0.86 | CHRM4 (0.32) | — | |
| SCHEMBL24317599 | 0.85 | — | — | |
| SCHEMBL26620392 | 0.81 | — | — | |
| SCHEMBL20154538 | 0.77 | — | — | |
| SCHEMBL16508758 | 0.76 | KDM4E (0.33) | — | |
| SCHEMBL26381406 | 0.74 | — | — | |
| SCHEMBL683603 | 0.73 | — | — | |
| SCHEMBL10034980 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL20152041 | 0.71 | — | — | |
| SCHEMBL20147310 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283263-A1 | CITRATE SALT, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME | FOGHORN THERAPEUTICS INC. (US) | 2023-01-12 | — | — | WO | disclosed |